Analytical Data
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基因名
Alk-Smase
- Application
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别名
Alk-Smase；Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UWV6
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表达区间
1-458aa
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氨基酸序列
MRGPAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALPPDGRPTLLPKGRSALPPSSRPLLVMGLLGTVILLSEVA
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Alk-SMase (alkaline sphingomyelinase) is an important enzyme that catalyzes the hydrolysis of sphingomyelin into ceramide and phosphocholine, playing a significant role in cellular signaling, membrane dynamics, and apoptosis. Abnormal regulation of Alk-SMase has been implicated in various diseases, including cancer and neurodegenerative disorders. Research has focused on understanding the structure and function of Alk-SMase, which aids in elucidating its mechanisms of action and regulatory pathways. The recombinant production of Alk-SMase allows for detailed biochemical characterization and facilitates studies on its interactions with other cellular components. Furthermore, the use of recombinant proteins in therapeutic applications holds promise for developing novel treatments targeting sphingolipid metabolism. By advancing our understanding of Alk-SMase through recombinant technology, researchers aim to harness its potential for innovative therapeutic strategies and improve our ability to address related diseases.
