Analytical Data
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基因名
CCT6B
- Application
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别名
CCT6B; T-complex Protein 1 subunit zeta-2; TCP-1-zeta-2; CCT-zeta-2; CCT-zeta-like; TCP-1-zeta-like; Testis-specific Tcp20; Testis-specific Protein TSA303
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92526
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表达区间
1-530aa
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氨基酸序列
MAAIKAVNSKAEVARAQAALAVNICAARGLQDVLRTNLGPKGTMKMLASGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
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分子量
84.04 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCT6B, or Chaperonin Containing TCP1 Subunit 6B, is a critical component of the cytosolic chaperonin complex, which plays a pivotal role in the proper folding and assembly of nascent polypeptides in eukaryotic cells. Recent research has highlighted the importance of CCT6B in various cellular processes, including stress response, protein quality control, and the assembly of multi-subunit protein complexes. Aberrant expression of CCT6B has been linked to several diseases, including cancer, neurodegeneration, and metabolic disorders, underscoring its potential as a therapeutic target. As scientists continue to unravel the complex interactions involving CCT6B, there is growing interest in its structural and functional characterization, particularly through the development of recombinant protein systems. By producing CCT6B as a recombinant protein, researchers can study its molecular mechanisms, investigate its interactions with client proteins, and explore its role in the chaperonin machinery in greater detail. This research not only enhances our understanding of protein folding pathways but also provides insights into how disruptions in these processes may lead to disease, paving the way for innovative approaches in drug design and therapeutic interventions. The ongoing study of CCT6B as a recombinant protein thus holds promise for elucidating fundamental biological processes and contributing to novel strategies for combating diseases associated with protein misfolding.
