Analytical Data
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基因名
ROD1
- Application
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别名
DKFZp781I1117; Fission yeast differentiation regulator; OTTHUMP00000021931; OTTHUMP00000021932; Polypyrimidine tract binding protein 3; regulator of differentiation 1; Regulator of differentiation (in S. pombe) 1; Regulator of differentiation 1; ROD 1; Rod1; ROD1 regulator of differentiation 1; ROD1_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95758
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表达区间
1-552 aa
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氨基酸序列
MDGVVTDLIT VGLKRGSDEL LSSGIINGPF TMNSSTPSTA NGNDSKKFKR DRPPCSPSRV LHLRKIPCDV TEAEIISLGL PFGKVTNLLM LKGKSQAFLE MASEEAAVTM VNYYTPITPH LRSQPVYIQY SNHRELKTDN LPNQARAQAA LQAVSAVQSG SLALSGGPSN EGTVLPGQSP VLRIIIENLF YPVTLEVLHQ IFSKFGTVLK IITFTKNNQF QALLQYADPV NAHYAKMALD GQNIYNACCT LRIDFSKLTS LNVKYNNDKS RDFTRLDLPT GDGQPSLEPP MAAAFGAPGI ISSPYAGAAG FAPAIGFPQA TGLSVPAVPG ALGPLTITSS AVTGRMAIPG ASGIPGNSVL LVTNLNPDLI TPHGLFILFG VYGDVHRVKI MFNKKENALV QMADANQAQL AMNHLSGQRL YGKVLRATLS KHQAVQLPRE GQEDQGLTKD FSNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVTVDD LKNLFIEAGC SVKAFKFFQK DRKMALIQLG SVEEAIQALI ELHNHDLGEN HHLRVSFSKS TI
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分子量
59.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ROD1 is a protein that has garnered interest in the field of molecular biology due to its role in modulating various cellular processes, particularly in the context of cancer research. Initially identified as a component involved in the regulation of RNA metabolism, ROD1 has been implicated in the control of gene expression and splicing, making it an important player in post-transcriptional regulation. Recent studies have highlighted its potential involvement in tumorigenesis, where altered ROD1 expression patterns have been associated with various cancers. The ability to manipulate ROD1 through recombinant protein techniques allows researchers to explore its functional mechanisms in greater depth. By expressing ROD1 in a controlled laboratory setting, scientists can investigate its interactions with other cellular proteins and RNA molecules, providing insights into the pathways it influences. Understanding ROD1's role in cellular functions not only contributes to the foundational knowledge of gene regulation but also opens avenues for the development of therapeutic strategies aimed at targeting aberrant ROD1 expression in cancer. Overall, ROD1 represents a promising subject for further research, with implications for both fundamental biology and medical applications.
