Analytical Data
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基因名
CCL3L3
- Application
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别名
464.2; C-C motif chemokine 3-like 1; CCL3L3; CL3L1_HUMAN; D17S1718; G0/G1 switch regulatory Protein 19-2; G0S19-2; LD78; LD78-beta(1-70); LD78-beta(5-70); LD78BETA; PAT 464.2; SCYA3L; SCYA3L1; Small-inducible cytokine A3-like 1; Tonsillar lymphocyte LD78 beta Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P16619
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表达区间
24-93aa
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氨基酸序列
APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA
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分子量
7.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL3L3, also known as macrophage inflammatory protein-1 gamma, is a chemokine that plays a crucial role in the immune response and has been implicated in various inflammatory diseases and conditions, including cancer and autoimmune disorders. This protein is part of a larger family of CC chemokines, which are involved in the recruitment of immune cells to sites of inflammation. Research into CCL3L3 has been motivated by its potential as a therapeutic target and biomarker for disease progression, given its ability to modulate the immune environment. Studies have shown that CCL3L3 can influence the behavior of various immune cells, such as T cells and macrophages, thus contributing to the pathophysiology of inflammatory responses. The recombinant production of CCL3L3 facilitates detailed studies into its structure-function relationships and interactions with cell surface receptors, paving the way for the development of targeted therapies. Furthermore, understanding the biological activities of CCL3L3 can provide insights into its role in both innate and adaptive immunity, enhancing our comprehension of immune regulation and inflammation. As research advances, CCL3L3 may emerge as a pivotal player in novel therapeutic approaches for inflammatory diseases, emphasizing the need for continued exploration of its biological functions and therapeutic implications.
