Analytical Data
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基因名
CD53
- Application
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别名
CD53;MOX44;TSPAN25;Leukocyte surface antigen CD53
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种属
Mouse
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q61451
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表达区间
107-181aa
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氨基酸序列
EQKLNTLVAE GLNDSIQHYH SDNSTMKAWD FIQTQLQCCG VNGSSDWTSG PPSSCPSGAD VQGCYNKAKS WFHSN
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分子量
11 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD53 is a tetraspanin protein that plays a crucial role in the regulation of immune cell functions and signaling pathways. Research has shown that CD53 is involved in various biological processes, including cell adhesion, migration, and activation, making it a significant focus in immunology and cancer research. Tetraspanins like CD53 are known to organize and stabilize membrane microdomains, allowing for the efficient interaction of various receptors and signaling molecules. Studies have reported that CD53 expression levels can influence immune responses and impact the progression of certain diseases, including autoimmune disorders and cancers. The recombinant expression of CD53 provides a valuable tool for elucidating its functional roles and interactions within the immune system. By generating CD53 proteins through recombinant techniques, researchers can investigate its structural properties, binding partners, and pathways in greater detail, contributing to a better understanding of its implications in health and disease. Such in-depth studies are essential for exploring the potential of CD53 as a therapeutic target, particularly in the context of enhancing immune responses against tumors or modulating inappropriate immune activation in autoimmune conditions. As the scientific community continues to delve deeper into the functions of tetraspanins, CD53 remains a promising candidate for unlocking new avenues in immunotherapy and precision medicine.












