Analytical Data
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基因名
CCDC49
- Application
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别名
Pre-mRNA-splicing factor CWC25 homolog. Coiled-coil domain-containing Protein 49. Spliceosome-associated Protein homolog CWC25
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NXE8
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表达区间
1-425aa
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氨基酸序列
MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR
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分子量
76 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC49 (Coiled-Coil Domain Containing 49) is a protein that has garnered interest in recent years due to its potential involvement in various cellular processes and its implications in human health and disease. Characterized by a coiled-coil structure, CCDC49 is suspected to play a role in the formation of protein complexes, contributing to cellular architecture and signaling pathways. Initial research indicates that CCDC49 may be implicated in cytoskeletal organization, which is crucial for maintaining cell shape and facilitating cellular movement. Moreover, studies have suggested that alterations in CCDC49 expression are associated with certain cancers and developmental disorders, prompting investigations into its function as a potential biomarker or therapeutic target. The recombinant expression of CCDC49 allows researchers to delve deeper into its biological mechanisms, providing a platform for studying its interaction with other proteins and cellular components. As a result, the study of recombinant CCDC49 not only enhances our understanding of its role in normal physiology but also offers insights into its contributions to pathophysiological conditions, making it a significant focus in the field of molecular biology and biomedical research.
