Cat: PA2000-6500

Recombinant Human CCDC38 Protein,GST

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Analytical Data

  • Gene name

    CCDC38

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CCDC38Coiled-coil domain-containing Protein 38

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q502W7

  • Expression Region

    1-563aa

  • AA Sequence

    MSSNLLPTLN SGGKVKDGST KEDRPYKIFF RDLFLVKENE MAAKETEKFM NRNMKVYQKT TFSSRMKSHS YLSQLAFYPK RSGRSFEKFG PGPAPIPRLI EGSDTKRTVH EFINDQRDRF LLEYALSTKR NTIKKFEKDI AMRERQLKKA EKKLQDDALA FEEFLRENDQ RSVDALKMAA QETINKLQMT AELKKASMEV QAVKSEIAKT EFLLREYMKY GFFLLQMSPK HWQIQQALKR AQASKSKANI ILPKILAKLS LHSSNKEGIL EESGRTAVLS EDASQGRDSQ GKPSRSLTRT PEKKKSNLAE SFGSEDSLEF LLDDEMDVDL EPALYFKEPE ELLQVLRELE EQNLTLFQYS QDVDENLEEV NKREKVIQDK TNSNIEFLLE QEKMLKANCV REEEKAAELQ LKSKLFSFGE FNSDAQEILI DSLSKKITQV YKVCIGDAED DGLNPIQKLV KVESRLVELC DLIESIPKEN VEAIERMKQK EWRQKFRDEK MKEKQRHQQE RLKAALEKAV AQPKKKLGRR LVFHSKPPSG NKQQLPLVNE TKTKSQEEEY FFT

  • Molecular Weight

    91.7 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

CCDC38, or coiled-coil domain containing 38, is a protein that has gained attention in recent years due to its potential roles in important cellular processes, including cell division and ciliary function. Research has indicated that CCDC38 may play a crucial role in the regulation of cilia, which are essential for cellular signaling and movement. Mutations or dysregulation of CCDC38 have been associated with various developmental disorders and diseases, making it a compelling target for further investigation. The production of recombinant CCDC38 protein allows researchers to explore its structural characteristics, interactions with other proteins, and downstream effects in cellular pathways. By studying this protein in detail, scientists aim to elucidate its functional mechanisms and its implications in human health and disease. Understanding CCDC38's role at the molecular level could pave the way for developing novel therapeutic strategies for conditions linked to ciliary dysfunction and related pathologies. Furthermore, the ability to generate and manipulate recombinant CCDC38 would facilitate high-throughput screenings for small molecules that can modulate its activity, thereby expanding our knowledge of ciliary biology and its associated disorders.

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