Analytical Data
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Gene name
CCDC2
- Application
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Alternative Names
Ccdc2; CMG 1; CMG-1; Coiled-coil domain containing 2; Coiled-coil domain-containing Protein 2; IFT74; IFT74_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96LB3
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Expression Region
1-600aa
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AA Sequence
MASNHKSSAA RPVSRGGVGL TGRPPSGIRP LSGNIRVATA MPPGTARPGS RGCPIGTGGV LSSQIKVAHR PVTQQGLTGM KTGTKGPQRQ ILDKSYYLGL LRSKISELTT EVNKLQKGIE MYNQENSVYL SYEKRAETLA VEIKELQGQL ADYNMLVDKL NTNTEMEEVM NDYNMLKAQN DRETQSLDVI FTERQAKEKQ IRSVEEEIEQ EKQATDDIIK NMSFENQVKY LEMKTTNEKL LQELDTLQQQ LDSQNMKKES LEAEIAHSQV KQEAVLLHEK LYELESHRDQ MIAEDKSIGS PMEEREKLLK QIKDDNQEIA SMERQLTDTK EKINQFIEEI RQLDMDLEEH QGEMNQKYKE LKKREEHMDT FIETFEETKN QELKRKAQIE ANIVALLEHC SRNINRIEQI SSITNQELKM MQDDLNFKST EVQKSQSTAQ NLTSDIQRLQ LDLQKMELLE SKMTEEQHSL KSKIKQMTTD LEIYNDLPAL KSSGEEKIKK LHQERMILST HRNAFKKIME KQNIEYEALK TQLQENETHS QLTNLERKWQ HLEQNNFAMK EFIATKSQES DYQPIKKNVT KQIAEYNKTI VDALHSTSGN
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Molecular Weight
69.2 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC2 (Coiled-Coil Domain Containing 2) is a gene encoding a protein that plays a crucial role in cellular processes, particularly in cilia formation and function. Cilia are essential organelles involved in various signaling pathways, and defects in ciliary proteins have been associated with a range of diseases, including ciliopathies, which can lead to issues such as renal dysplasia, infertility, and respiratory problems. Research into the recombinant CCDC2 protein aims to elucidate its specific functions and interactions within the ciliary structure, thereby enhancing our understanding of ciliary dynamics and the molecular mechanisms behind related disorders. By producing and analyzing recombinant CCDC2, researchers can investigate its role in protein complexes involved in cilia assembly and maintenance, offering insights into potential therapeutic targets for ciliary dysfunction. Additionally, studying CCDC2 in model organisms could further reveal its biological significance, paving the way for novel interventions in cilia-related diseases. Therefore, the exploration of CCDC2's recombinant protein is vital not only for basic science but also for the development of clinical applications addressing inherited and acquired ciliary diseases.
