Analytical Data
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基因名
CCDC16
- Application
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别名
ZNF830; CCDC16; Zinc finger Protein 830; Coiled-coil domain-containing Protein 16
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96NB3
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表达区间
1-372aa
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氨基酸序列
MASSASARTPAGKRVINQEELRRLMKEKQRLSTSRKRIESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLGKQHREKVAELKGAKEASQGSSASSAPQSVKRKAPDADDQDVKRAKATLVPQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDLLSQDWRVKGALL
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分子量
68.4 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC16, or coiled-coil domain containing 16, is a protein that has garnered interest due to its potential roles in cellular processes and disease mechanisms. Initially identified as a component involved in the regulation of endosomal trafficking, CCDC16 has also been implicated in the modulation of protein homeostasis and autophagy. Dysregulation of CCDC16 has been linked to various pathologies, including neurodegenerative diseases and certain types of cancers. In particular, research suggests that altered expression or function of CCDC16 can impact cellular responses to stress and affect the degradation of misfolded proteins, highlighting its significance in maintaining cellular health. Furthermore, studies indicate that CCDC16 might interact with various signaling pathways, making it a potential target for therapeutic interventions. Despite these intriguing associations, the full mechanism of action and the precise biological functions of CCDC16 remain to be elucidated. Thus, the recombinant expression of CCDC16 protein is crucial for in-depth studies, allowing researchers to investigate its structural features, interactions with other cellular components, and its overall role in health and disease. This ongoing research presents opportunities not only for understanding fundamental cellular biology but also for developing new strategies to treat diseases linked to CCDC16 dysregulation.
