Analytical Data
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Gene name
CCDC15
- Application
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Alternative Names
CCDC15Coiled-coil domain-containing Protein 15
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q0P6D6
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Expression Region
1-465aa
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AA Sequence
MLGSMARKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVEPASPGSSEIPAYTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSSATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILP
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Molecular Weight
79 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC15, or Coiled-Coil Domain Containing 15, is a protein that has garnered attention due to its significant role in cellular processes and potential involvement in various diseases. Initially identified in studies focused on the homologous recombination repair pathway, CCDC15 is believed to play a critical role in maintaining genome stability. Recent research has suggested that it may be involved in the regulation of autophagy, a process crucial for cellular degradation and recycling, which has implications for cancer biology and neurodegenerative diseases. Furthermore, alterations in the expression or function of CCDC15 have been associated with certain genetic disorders and cancer progression, making it a promising target for therapeutic intervention. The study of recombinant CCDC15 protein offers valuable insights into its structure-function relationships and cellular functions through protein-protein interaction analyses and functional assays. Understanding CCDC15 through recombinant protein technology can lead to the discovery of novel biomarkers and therapeutic targets, advancing our knowledge of disease mechanisms and potentially paving the way for innovative treatment strategies. Overall, the research on CCDC15 and its recombinant protein provides a crucial foundation for elucidating its role in human health and disease, highlighting the importance of this protein in fundamental biological processes.
