Analytical Data
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Gene name
CARKL
- Application
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Alternative Names
Carbohydrate kinase like; Carbohydrate kinase like Protein ; Carbohydrate kinase-like Protein; CARKL; Sedoheptulokinase; SHK; Shpk; SHPK_HUMAN
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UHJ6
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Expression Region
1-478aa
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AA Sequence
MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHDYVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDPTAPVAYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQQRDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPIQQLQEWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLRRHLNQKES
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Molecular Weight
77.9 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CARKL (Carnitine Acylcarnitine translocase-like protein) is a protein that plays a significant role in fatty acid transport and energy metabolism within cells. Recent studies have shown that CARKL is involved in various metabolic processes, including the regulation of mitochondrial function and the modulation of cellular responses to stress. As obesity and metabolic disorders become increasingly prevalent in modern society, understanding the role of proteins like CARKL in energy homeostasis has gained considerable attention. Research has suggested that CARKL may influence the development of insulin resistance and other metabolic syndromes, highlighting its potential as a therapeutic target. The recombinant expression of CARKL in laboratory settings allows researchers to study its structural and functional properties, providing insights into its mechanism of action and interaction with other cellular components. By unraveling the biochemical pathways associated with CARKL, scientists aim to identify novel intervention strategies for combating metabolic diseases, making this research area critical for improving public health outcomes.
