Analytical Data
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Gene name
Rgr
- Application
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Alternative Names
RGR; RPE-retinal G protein-coupled receptor
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P47804
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AA Sequence
MAETSALPTGFGELEVLAVGMVLLVEALSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRRWPYGSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLMEQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSISPKLQMVPALIAKMVPTINAINYALGNEMVCRGIWQCLSPQKREKDRTK
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Molecular Weight
31.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Rgr, or retinoid G protein-coupled receptor, is a member of the G protein-coupled receptor (GPCR) family, which plays a crucial role in various physiological processes, including vision, metabolism, and immune response. The study of Rgr and its recombinant proteins has gained significant interest in the field of molecular biology due to its potential implications in understanding retinal diseases and metabolic disorders. Recombinant Rgr proteins are produced through genetic engineering techniques, allowing for the analysis of their structure, function, and interaction with ligands. Research has revealed that Rgr is involved in the visual cycle, particularly in the regeneration of retinal chromophore, a vital component for phototransduction in photoreceptor cells. Furthermore, Rgr's unique properties may contribute to understanding its signaling pathways, which could lead to novel therapeutic strategies for conditions like retinitis pigmentosa and age-related macular degeneration. By utilizing recombinant Rgr proteins, scientists aim to unravel the complexities of its functional roles, paving the way for advancements in targeted treatments and enhancing our overall understanding of GPCR-mediated signaling. Overall, the investigation of Rgr recombinant proteins is crucial for leveraging their biological significance and therapeutic potential in vision-related research and beyond.
