Analytical Data
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基因名
PLTP
- Application
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别名
PLTP；Phospholipid transfer Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55058
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表达区间
19-441aa
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氨基酸序列
FPGCKIRVTSKALELVKQEGLRFLEQELETITIPDLRGKEGHFYYNISEV KVTELQLTSSELDFQPQQELMLQITNASLGLRFRRQLLYWFLKVYDFLST FITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRSSVDELVGIDYSLM KDPVASTSNLDMDFRGAFFPLTERNWSLPNRAVEPQLQEEERMVYVAFSE FFFDSAMESYFRAGALQLLLVGDKVPHDLDMLLRATYFGSIVLLSPAVID SPLKLELRVLAPPRCTIKPSGTTISVTASVTIALVPPDQPEVQLSSMTMD ARLSAKMALRGKALRTQLDLRRFRIYSNHSALESLALIPLQAPLKTMLQI GVMPMLNERTWRGVQIPLPEGINFVHEVVTNHAGFLTIGADLHFAKGLRE VIEKNRPADVRASTAPTPSTAAV
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分子量
72 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLTP, or phospholipid transfer protein, is a significant protein implicated in lipid metabolism and lipoprotein metabolism. Research into PLTP has gained momentum due to its critical role in transferring phospholipids between lipoproteins, thereby influencing the composition and functionality of lipoproteins. Dysregulation of PLTP has been associated with various cardiovascular diseases, metabolic disorders, and conditions related to obesity and diabetes, making it a potential target for therapeutic interventions. Additionally, PLTP is involved in the process of high-density lipoprotein (HDL) remodeling, which is essential for cholesterol efflux and reverse cholesterol transport. As a result, understanding the molecular mechanisms underlying PLTP function and its interactions with other proteins and lipids is crucial for developing strategies to modulate its activity. Moreover, researchers are exploring PLTP as a biomarker for lipid-related diseases, which further emphasizes the need for comprehensive studies on its structure, function, and potential implications in health and disease. This ongoing research aims to unravel the complexities of PLTP, providing insights that could lead to novel therapeutic avenues in managing lipid-related conditions.
