Analytical Data
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基因名
C9orf97
- Application
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别名
C9orf97; PP4189; Rhodanese domain-containing Protein 2; RP11-244N9.5; Thiosulfate sulfurtransferase/rhodanese-like domain-containing Protein 2; Tstd2; TSTD2_HUMAN
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5T7W7
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表达区间
1-489aa
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氨基酸序列
MSLINPSSSLKAELDGSTKKKYSFAKKKAFALFVKTKEVPTKRSFECKEKLWKCCQQLFTDQTSIHRHVATQHADEIYHQTASILKQLAVTLSTSKSLSSADEKNPLKECLPHSHDVSAWLPDISCFNPDELISGQGSEEGEVLLYYCYHDLEDPQWICAWQTALCQHLHLTGKIRIAAEGINGTVGGSKLATRLYVEVMLSFPLFKDDLCKDDFKTSKGGAHCFPELRVGVFEEIVPMGISPKKISYKKPGIHLSPGEFHKEVEKFLSQANQEQSDTILLDCRNFYESKIGRFQGCLAPDIRKFSYFPSYVDKNLELFREKRVLMYCTGGIRCERGSAYLKAKGVCKEVFQLKGGIHKYLEEFPDGFYKGKLFVFDERYALSYNSDVVSECSYCGARWDQYKLCSTPQCRQLVLTCPACQGQGFTACCVTCQDKGSRKVSGPMQDSFKEECECTARRPRIPRELLQHVRQPVSPEPGPDADEDGPVLM
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分子量
81.6 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C9orf98, a gene located on chromosome 9, encodes a protein that has been implicated in various cellular processes, including cell signaling and development. Recent studies have highlighted its potential role in neurodegenerative diseases, particularly in the context of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), where mutations in the gene can lead to dysregulation of RNA metabolism and cellular homeostasis. Research has focused on the recombinant expression of C9orf98 to elucidate its functional properties and interactions with other proteins, as well as to explore its potential as a biomarker for these diseases. By utilizing advanced biochemical techniques, scientists aim to characterize the protein's structure, determine its binding partners, and understand its role in neuronal cell fate. This study of C9orf98 recombinant protein not only contributes to the basic understanding of its biological functions but also has implications for the development of therapeutic strategies targeting the molecular pathways involved in neurodegeneration. Overall, the investigation into C9orf98 is crucial for unraveling the complexities of ALS and FTD, advancing our knowledge, and potentially leading to new treatment paradigms for these debilitating conditions.
