Analytical Data
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Gene name
RDH10
- Application
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Alternative Names
RDH 10; RDH10; RDH10_HUMAN; Retinol dehydrogenase 10 (all trans); Retinol dehydrogenase 10; SDR16C4; Short chain dehydrogenase/reductase family 16C member 4
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IZV5
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Expression Region
1-341 aa
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AA Sequence
MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI
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Molecular Weight
64.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RDH10 (Retinol Dehydrogenase 10) is an important enzyme in the retinoid metabolism pathway, playing a crucial role in the conversion of retinaldehyde to retinol, a key vitamin A derivative essential for various physiological processes, including vision, cell growth, and differentiation. Research on RDH10 has gained significance due to its involvement in several biological functions and potential implications in health and disease. Mutations or dysregulation of RDH10 have been linked to congenital disorders, particularly those affecting vision, as well as other systemic effects that may arise from impaired retinoid signaling. The study of RDH10 recombinant proteins enables researchers to investigate the enzyme's biophysical properties, substrate specificity, and catalytic mechanisms. These efforts contribute to a deeper understanding of retinoid metabolism and the potential therapeutic strategies for conditions associated with RDH10 malfunction. In recent years, advancements in recombinant protein technology have facilitated the production and functional characterization of RDH10, allowing scientists to explore its roles in various biological contexts and to develop targeted interventions that address retinoid-related disorders.
