Analytical Data
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基因名
HWP1
- Application
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别名
HWP1；ECE2；Hyphal wall Protein 1
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种属
Candida albicans
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P46593
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表达区间
27-203aa
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氨基酸序列
GQGETEEALIQKRSYDYYQEPCDDYPQQQQQQEPCDYPQQQQQEEPCDYPQQQPQEPCDYPQQPQEPCDYPQQPQEPCDYPQQPQEPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDVPCDNPPQPDQPDDNPPIPNIPTDWIPNIPTDWIPDIPEKPTTPATTPNIPA
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分子量
21.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HWP1, or Hyphal Wall Protein 1, is a key protein found in various fungi, particularly in the pathogenic species of the Candida genus. Its primary function involves maintaining cell wall integrity during the hyphal growth phase, which is crucial for the virulence of these organisms. Research has shown that HWP1 is involved in adherence and biofilm formation, making it a significant factor in the pathogenicity of Candida albicans, a common cause of opportunistic infections in immunocompromised individuals. The study of HWP1 has garnered attention due to its potential as a therapeutic target; understanding its structure and function can lead to the development of antifungal strategies. Additionally, HWP1 serves as a model for exploring fungal biology, pathogenesis, and host interactions, shedding light on the mechanisms fungi employ to survive and thrive within host environments. Thus, HWP1 research not only aids in combating fungal infections but also enriches our comprehension of fungal physiology and host-pathogen dynamics.
