Analytical Data
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Gene name
RBM6
- Application
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Alternative Names
3G2 ; 4930506F14Rik; DEF 3 ; DEF3 ; DKFZp686B0877 ; FLJ36517; g16; HLC 11; KIAA4015; Lung cancer antigen NY LU 12 ; Lung cancer antigen NY-LU-12; Lung cancer protooncogene 11; mKIAA4015; NY LU 12; Protein G16; RBM6; RBM6/RBM5 fusion; RBM6_HUMAN; RGD1560367; RNA binding motif protein 6 ; RNA-binding motif protein 6; RNA-binding protein 6; RNA-binding protein DEF-3
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P78332
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Expression Region
1-601 aa
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AA Sequence
MIQDKEVTLEYVSSLDFWYCKRCKANIGGHRSSCSFCKNPREVTEAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKREAERYLPPSRREGPTFRRDRERESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRLTTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKKDRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIKHQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKRIKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMRGPSVGASGRTSKRQSNETYRDAVRRVMFARYKELD
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Molecular Weight
95.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RBM6 (RNA-binding motif protein 6) is a member of the RNA-binding protein family, which plays a critical role in post-transcriptional regulation of gene expression. Recent studies have highlighted its involvement in various biological processes, including alternative splicing, RNA stability, and cell proliferation. Importantly, RBM6 has been implicated in cancer biology, as its expression levels can influence tumorigenesis and progression in several cancer types. Given its potential as a therapeutic target and biomarker, the characterization of RBM6, particularly in the context of recombinant protein studies, has gained significant attention. Researchers have focused on expressing and purifying recombinant RBM6 to elucidate its functional mechanisms and interactions at the molecular level. Additionally, understanding the structure-function relationship of RBM6 through recombinant techniques can provide insights into its role in cellular processes and disease states. These investigations are crucial for evaluating RBM6's potential utility in clinical applications, especially in targeted therapies and diagnostics. Overall, the research on RBM6 recombinant protein is not only essential for deciphering its biological functions but also offers promise for the development of innovative strategies in cancer treatment and management.
