Analytical Data
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Gene name
RBM4B
- Application
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Alternative Names
MGC10871; RBM30; RBM4B; RBM4B_HUMAN; RBM4L; RNA binding protein 4B; RNA-binding motif protein 30; RNA-binding motif protein 4B; RNA-binding protein 30; RNA-binding protein 4B; ZCCHC15; ZCRB3B; zinc finger CCHC-type and RNA binding motif 3B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BQ04
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Expression Region
1-359 aa
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AA Sequence
MVKLFIGNLP REATEQEIRS LFEQYGKVLE CDIIKNYGFV HIEDKTAAED AIRNLHHYKL HGVNINVEAS KNKSKASTKL HVGNISPTCT NQELRAKFEE YGPVIECDIV KDYAFVHMER AEDAVEAIRG LDNTEFQGKR MHVQLSTSRL RTAPGMGDQS GCYRCGKEGH WSKECPVDRT GRVADFTEQY NEQYGAVRTP YTMGYGESMY YNDAYGALDY YKRYRVRSYE AVAAAAAASA YNYAEQTMSH LPQVQSTTVT SHLNSTSVDP YDRHLLPNSG AAATSAAMAA AAATTSSYYG RDRSPLRRAA AMLPTVGEGY GYGPESELSQ ASAATRNSLY DMARYEREQY VDRARYSAF
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Molecular Weight
40.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RBM4B, or RNA-binding motif protein 4B, is a member of the RNA-binding protein family, which plays a crucial role in various cellular processes, including RNA splicing, stability, and translation regulation. The interest in RBM4B has surged due to its potential involvement in cancer biology and other diseases, as altered expression levels have been observed in various tumor types. Research indicates that RBM4B may impact cell proliferation, apoptosis, and differentiation by modulating the expression of specific target genes. Additionally, its interactions with other proteins and RNA molecules suggest that it may function in complex regulatory networks. The recombinant expression of RBM4B in a laboratory setting allows for detailed study of its biochemical properties, functional mechanisms, and interactions, facilitating the exploration of its role in health and disease. This research could pave the way for new therapeutic strategies targeting RBM4B-related pathways, making it a compelling subject for ongoing studies in molecular biology and cancer research.
