Analytical Data
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Gene name
RASD1
- Application
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Alternative Names
Activator of G protein signaling 1; Activator of G protein signaling; Activator of G-protein signaling 1; AGS 1; AGS1; Dexamethasone induced ras related protein 1; Dexamethasone-induced ras protein 1; Dexamethasone-induced Ras-related protein 1; Dexras 1; MGC:26290; RAS dexamethasone induced 1; Ras protein; Dexamethasone-induced; 1; Ras related protein; RASD 1; Rasd1; RASD1_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y272
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Expression Region
1-278 aa
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AA Sequence
MKLAAMIKKM CPSDSELSIP AKNCYRMVIL GSSKVGKTAI VSRFLTGRFE DAYTPTIEDF HRKFYSIRGE VYQLDILDTS GNHPFPAMRR LSILTGDVFI LVFSLDNRDS FEEVQRLRQQ ILDTKSCLKN KTKENVDVPL VICGNKGDRD FYREVDQREI EQLVGDDPQR CAYFEISAKK NSSLDQMFRA LFAMAKLPSE MSPDLHRKVS VQYCDVLHKK ALRNKKLLRA GSGGGGGDPG DAFGIVAPFA RRPSVHSDLM YIREKASAGS QAKDKERC
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Molecular Weight
31.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RASD1 (Ras DomaIn Containing 1) is a member of the Ras superfamily of small GTPases, which are critical regulators of various cellular processes including proliferation, differentiation, and apoptosis. Research on RASD1 has gained attention due to its unique role in cellular signaling pathways and its potential implications in cancer and neurodegenerative diseases. Unlike other Ras proteins, RASD1 is characterized by its unique expression pattern and function, serving as a negative regulator in some signaling cascades. It is particularly noted for its involvement in the regulation of neuronal development and response to stress, making it a target of interest in brain-related pathologies. Additionally, RASD1 has been implicated in the modulation of immune responses, suggesting its role in various physiological and pathological processes. The production and study of RASD1 recombinant proteins have enabled scientists to investigate its biochemical properties, interactions with effector proteins, and functional roles in cellular signaling networks. Understanding the mechanisms by which RASD1 exerts its effects can provide valuable insights into its potential as a therapeutic target and could aid in the development of novel strategies for the treatment of diseases associated with dysregulated GTPase activity. The ongoing research is aimed at elucidating the precise molecular mechanisms underlying RASD1 function and its potential therapeutic applications in oncology and neurology.
