Cat: PA2000-6320

Recombinant Human C6orf4 Protein,GST

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Analytical Data

  • Gene name

    C6orf4

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Act 1; ACT1; Activator of cAMP responsive element modulator (CREM) in testis; Adapter Protein CIKS; C6ORF4; C6ORF5; C6ORF6; Chromosome 6 Open Reading Frame 4; Chromosome 6 Open Reading Frame 5; Chromosome 6 Open Reading Frame 6

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O43734

  • Expression Region

    1-574aa

  • AA Sequence

    MPPQLQETRM NRSIPVEVDE SEPYPSQLLK PIPEYSPEEE SEPPAPNIRN MAPNSLSAPT MLHNSSGDFS QAHSTLKLAN HQRPVSRQVT CLRTQVLEDS EDSFCRRHPG LGKAFPSGCS AVSEPASESV VGALPAEHQF SFMEKRNQWL VSQLSAASPD TGHDSDKSDQ SLPNASADSL GGSQEMVQRP QPHRNRAGLD LPTIDTGYDS QPQDVLGIRQ LERPLPLTSV CYPQDLPRPL RSREFPQFEP QRYPACAQML PPNLSPHAPW NYHYHCPGSP DHQVPYGHDY PRAAYQQVIQ PALPGQPLPG ASVRGLHPVQ KVILNYPSPW DHEERPAQRD CSFPGLPRHQ DQPHHQPPNR AGAPGESLEC PAELRPQVPQ PPSPAAVPRP PSNPPARGTL KTSNLPEELR KVFITYSMDT AMEVVKFVNF LLVNGFQTAI DIFEDRIRGI DIIKWMERYL RDKTVMIIVA ISPKYKQDVE GAESQLDEDE HGLHTKYIHR MMQIEFIKQG SMNFRFIPVL FPNAKKEHVP TWLQNTHVYS WPKNKKNILL RLLREEEYVA PPRGPLPTLQ VVPL

  • Molecular Weight

    64.6 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

C6orf4, also known as Chromosome 6 Open Reading Frame 4, has emerged as a protein of interest in various biomedical research contexts due to its potential roles in cellular processes and disease mechanisms. Initially characterized through genomic studies, C6orf4's function remains largely elusive, but emerging evidence suggests it may be involved in cell signaling, apoptosis, and immune responses. Moreover, studies have linked C6orf4 expression to cancer, indicating a possible role in tumorigenesis and metastasis. The recombinant expression of C6orf4 in heterologous systems has facilitated the study of its structural and functional properties, enabling researchers to investigate its interactions with other proteins and its influence on cellular pathways. Moreover, understanding the post-translational modifications of C6orf4, such as phosphorylation or glycosylation, is crucial as these modifications may significantly impact its activity and functionality. Recent advancements in proteomics and molecular biology tools have paved the way for detailed analyses of C6orf4, offering insights that could enhance our understanding of its biological significance. Thus, the study of C6orf4 recombinant protein not only contributes to the fundamental knowledge of this enigmatic protein but also holds potential implications for therapeutic strategies targeting related diseases.

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