Analytical Data
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基因名
CDC42BPB
- Application
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别名
CDC42BPB；KIAA1124；Serine/threonine-Protein kinase MRCK beta
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y5S2
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDC42BPB, also known as KIAA0725, is a member of the CDC42-binding protein family that plays a crucial role in a variety of cellular processes, including cell signaling, cytoskeletal dynamics, and cell division. It functions as a downstream effector of the small GTPase CDC42, which is involved in regulating the organization of the actin cytoskeleton and influencing cell shape and motility. The aberrant regulation of CDC42BPB has been implicated in several pathological conditions, including cancer, where it may contribute to tumor progression and metastasis. Understanding the molecular mechanisms by which CDC42BPB operates is essential for elucidating its role in cellular homeostasis and disease. Recent studies have highlighted the potential for CDC42BPB to be a therapeutic target, making it significant for research in cancer biology and therapeutic development. Recombinant CDC42BPB proteins are used extensively in research to study its functional properties, interactions with other cellular proteins, and its influence on cellular behavior. Investigating CDC42BPB in various experimental models could provide insights into its mechanisms of action and potential implications for therapeutics in diseases characterized by dysregulated CDC42 signaling.
