Analytical Data
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基因名
RAB28
- Application
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别名
RAB28; Ras-related protein Rab-28
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51157
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表达区间
2-218 aa
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氨基酸序列
SDSEEESQD RQLKIVVLGD GASGKTSLTT CFAQETFGKQ YKQTIGLDFF LRRITLPGNL NVTLQIWDIG GQTIGGKMLD KYIYGAQGVL LVYDITNYQS FENLEDWYTV VKKVSEESET QPLVALVGNK IDLEHMRTIK PEKHLRFCQE NGFSSHFVSA KTGDSVFLCF QKVAAEILGI KLNKAEIEQS QRVVKADIVN YNQEPMSRTV NPPRSSMC
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分子量
24.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB28 is a member of the RAB family of small GTPases, which play crucial roles in intracellular trafficking and membrane dynamics. Initially identified in various tissues, RAB28 has garnered attention due to its potential involvement in regulating endosomal and lysosomal functions. Research indicates that RAB28 may be linked to essential cellular processes such as autophagy, organelle dynamics, and signal transduction. Its expression patterns suggest a role in neuronal development and function, making it a candidate for studies related to neurodegenerative diseases. The study of recombinant RAB28 protein aims to elucidate its functional properties, interactions with other cellular components, and the molecular mechanisms underlying its activity. By generating and characterizing recombinant RAB28, researchers can explore its GTPase activity, binding partners, and how it influences cellular pathways. Furthermore, understanding RAB28’s role may provide insights into its potential as a therapeutic target, particularly in conditions where cellular trafficking is disrupted. Overall, the investigation of recombinant RAB28 protein serves as a cornerstone in advancing our knowledge of RAB family dynamics and their implications in health and disease.
