Analytical Data
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Gene name
RAB15
- Application
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Alternative Names
RAB15
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P59190
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Expression Region
1-212 aa
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AA Sequence
MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRMRASNELALAELEEEEGKPEGPANSSKTCWC
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Molecular Weight
25.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB15 is a member of the RAB family of small GTPases, which play critical roles in intracellular vesicle trafficking and membrane dynamics. Research has shown that RAB proteins are implicated in various cellular processes, including endocytosis, exocytosis, and interactions with other proteins that regulate these pathways. RAB15, in particular, is expressed in a variety of tissues and has been linked to processes such as neuronal development and insulin signaling. Recent studies have highlighted its potential role in the pathogenesis of certain diseases, including cancer and neurological disorders. Given its importance in these biological processes, the preparation and characterization of RAB15 recombinant protein are crucial for understanding its function and mechanics at the molecular level. Researchers seek to investigate RAB15’s interaction partners and downstream signaling pathways, which could reveal insights into its contribution to cellular homeostasis and disease. Through the production of RAB15 recombinant protein, scientists aim to elucidate its structural and functional properties, paving the way for targeted therapeutic strategies that could modulate its activity in disease contexts. This line of research not only enhances our fundamental understanding of vesicular transport mechanisms but also opens up potential avenues for drug discovery and the development of novel treatment modalities.
