Cat: PA2000-6075

Recombinant Human C19orf51 Protein,GST

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Analytical Data

  • Gene name

    C19orf51

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Dynein axonemal assembly factor 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8N9W5

  • Expression Region

    1-541aa

  • AA Sequence

    MTTPAGSGSGFGSVSWWGLSPALDLQAESPPVDPDSQADTVHSNPELDVLLLGSVDGRHLLRTLSRAKFWPRRRFNFFVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLEVWGNALLRPPVAAFVRAQADLLAHLVPEPDRLEEQLPWLSLRALKFRERDALEAVFRFWAGGEKGPQAFPMSRLWDSRLRHYLGSRYDARRGVSDWDLRMKLHDRGAQVIHPQEFRRWRDTGVAFELRDSSAYHVPNRTLASGRLLSYRGERVAARGYWGDIATGPFVAFGIEADDESLLRTSNGQPVKTAGEITQHNVTELLRDVAAWGRARATGGDLEEQQHAEGSPEPGTPAAPTPESFTVHFLPLNSAQTLHHKSCYNGRFQLLYVACGMVHLLIPELGACVAPGGNLIVELARYLVDVRQEQLQGFNTRVRELAQAAGFAPQTGARPSETFARFCKSQESALGNTVPAVEPGTPPLDILAQPLEASNPALEGLTQPLQGGTPHCEPCQLPSESPGSLSEVLAQPQGALAPPNCESDSKTGV

  • Molecular Weight

    85.8 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

C19orf51, also known as the interferon-induced protein 44-like (IFI44L), has garnered significant attention in recent years due to its potential role in immune response and viral infections. Positioned on chromosome 19, this gene encodes a protein that is implicated in the regulation of immune signaling pathways, particularly those involving interferons, which are crucial for the host defense against pathogens. Research has shown that C19orf51 may play a role in modulating the activity of immune cells and influencing inflammation, making it a candidate for studies related to autoimmune diseases and infectious agents. Additionally, its involvement in the cellular response to stress and viral challenges underscores its importance in understanding the mechanisms of host-pathogen interactions. Advances in recombinant protein technology have enabled researchers to produce C19orf51 in heterologous systems, facilitating in vitro studies of its structure and function. This recombinant protein can be utilized in various assays to explore its interactions with other proteins and its downstream effects on immune responses. As scientists continue to elucidate the biological functions of C19orf51, the insights gained could pave the way for novel therapeutic approaches targeting immune modulation in diseases where the protein is dysregulated. The ongoing investigation into the role of C19orf51 in viral infections, particularly in the context of emerging pathogens, highlights its relevance in contemporary biomedical research and its potential implications for public health strategies.

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