Analytical Data
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Gene name
C19orf46
- Application
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Alternative Names
SYNE4; C19orf46; Nesprin-4; KASH domain-containing Protein 4; KASH4; Nuclear envelope spectrin repeat Protein 4
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N205
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Expression Region
1-291aa
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AA Sequence
MALSLPLGPRLGSEPLNHPPGAPREADIVGCTVCPASGEESTSPEQAQTLGQDSLGPPEHFQGGPRGNEPAAHPPRWSTPSSYEDPAGGKHCEVFEEANTLDQDLEVEGDSDWPGPGGVWGPWAPSSLPTSTELEWDPAGDIGGLGPLGQKTARTLGVPCELCGHRGPQGRGQGLEEADTSHSRQDMLESGLGHQKRLARHQRHSLLRKPQDKKRQASPHLQDVRLEGNPGAPDPASRQPLTFLLILFLLFLLLVGAMFLLPASGGPCCSHARIPRTPYLVLSYVNGLPPV
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Molecular Weight
57.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C19orf46, also known as "chromosome 19 open reading frame 46," is a gene located on chromosome 19 that has garnered interest in recent years due to its potential implications in cellular processes and disease mechanisms. Recent studies suggest that C19orf46 may play a crucial role in cellular growth, differentiation, and apoptosis, which are essential for maintaining tissue homeostasis and functionality. Despite its growing prominence in biomedical research, the specific biological functions of C19orf46 remain largely unexplored. The recombinant protein of C19orf46 is being investigated as a means to better understand its structure and function, with the aim of elucidating its role in various physiological and pathological contexts, such as cancer and neurodegenerative diseases. Researchers are focused on producing high-quality recombinant C19orf46 to analyze its interactions, localization, and effects on cellular pathways. This will help to clarify its putative involvement in signaling networks and provide insights into how its dysregulation could lead to disease. Further investigation into the recombinant C19orf46 protein is expected to shed light on its biological significance and potentially identify it as a novel therapeutic target or biomarker for various diseases.
