Analytical Data
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Gene name
C19orf21
- Application
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Alternative Names
chromosome 19 open reading frame 21; hypothetical Protein LOC126353; Misp; MISP_HUMAN; Mitotic interactor and substrate of PLK1; Mitotic spindle positioning Protein; Uncharacterized Protein C19orf21
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IVT2
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Expression Region
1-679aa
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AA Sequence
MDRVTRYPIL GIPQAHRGTG LVLDGDTSYT YHLVCMGPEA SGWGQDEPQT WPTDHRAQQG VQRQGVSYSV HAYTGQPSPR GLHSENREDE GWQVYRLGAR DAHQGRPTWA LRPEDGEDKE MKTYRLDAGD ADPRRLCDLE RERWAVIQGQ AVRKSSTVAT LQGTPDHGDP RTPGPPRSTP LEENVVDREQ IDFLAARQQF LSLEQANKGA PHSSPARGTP AGTTPGASQA PKAFNKPHLA NGHVVPIKPQ VKGVVREENK VRAVPTWASV QVVDDPGSLA SVESPGTPKE TPIEREIRLA QEREADLREQ RGLRQATDHQ ELVEIPTRPL LTKLSLITAP RRERGRPSLY VQRDIVQETQ REEDHRREGL HVGRASTPDW VSEGPQPGLR RALSSDSILS PAPDARAADP APEVRKVNRI PPDAYQPYLS PGTPQLEFSA FGAFGKPSSL STAEAKAATS PKATMSPRHL SESSGKPLST KQEASKPPRG CPQANRGVVR WEYFRLRPLR FRAPDEPQQA QVPHVWGWEV AGAPALRLQK SQSSDLLERE RESVLRREQE VAEERRNALF PEVFSPTPDE NSDQNSRSSS QASGITGSYS VSESPFFSPI HLHSNVAWTV EDPVDSAPPG QRKKEQWYAG INPSDGINSE VLEAIRVTRH KNAMAERWES RIYASEEDD
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Molecular Weight
101.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C19orf21, a protein-coding gene located on chromosome 19, has garnered attention in recent years due to its potential roles in various biological processes and diseases. Initially, its function was largely unknown, but emerging studies have suggested that C19orf21 may be involved in cellular signaling pathways, metabolism, and the regulation of gene expression. Research has indicated that alterations in C19orf21 expression could be linked to conditions such as cancer and neurodegenerative disorders, prompting scientists to investigate its precise molecular mechanisms. The production of recombinant C19orf21 protein has become a focal point for researchers aiming to elucidate its structure-function relationships and interactions with other cellular components. By utilizing techniques such as recombinant DNA technology and protein purification, scientists can generate sufficient quantities of C19orf21 to conduct functional assays and structural studies. These investigations aim to clarify its biological roles and explore its potential as a therapeutic target. Understanding the nuances of C19orf21's function could not only provide insights into fundamental cellular processes but also pave the way for novel strategies in disease treatment and prevention. As research progresses, the recombinant C19orf21 protein stands as a promising tool in delineating the complexities of this enigmatic protein and its implications in human health.
