Analytical Data
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Gene name
PTPN20B
- Application
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Alternative Names
TPN20; telomeric copy; bA142I17.1; bA42B19.1; cancer/testis antigen 126; CT126; hPTPN20; protein tyrosine phosphatase; non-receptor type 20B; PTN20_HUMAN; PTPN20; centromeric copy; PTPN20A; PTPN20B; Tyrosine-protein phosphatase non-receptor type 20
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q4JDL3
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Expression Region
1-420 aa
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AA Sequence
MSSPRDFRAE PVNDYEGNDS EAEDLNFRET LPSSSQENTP RSKVFENKVN SEKVKLSLRN FPHNDYEDVF EEPSESGSDP SMWTARGPFR RDRWSSEDEE AAGPSQALSP LLSDTRKIVS EGELDQLAQI RPLIFNFHEQ TAIKDCLKIL EEKTAAYDIM QEFMALELKN LPGEFNSGNQ PSNREKNRYR DILPYDSTRV PLGKSKDYIN ASYIRIVNCG EEYFYIATQG PLLSTIDDFW QMVLENNSNV IAMITREIEG GIIKCYHYWP ISLKKPLELK HFRVFLENYQ ILQYFIIRMF QVVEKSTGTS HSVKQLQFTK WPDHGTPASA DSFIKYIRYA RKSHLTGPMV VHCSAGIGRT GVFLCVDVVF CAIVKNCSFN IMDIVAQMRE QRSGMVQTKE QYHFCYDIVL EVLRKLLTLD
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Molecular Weight
48.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTPN20B is a member of the protein tyrosine phosphatase (PTP) family, which plays a critical role in various cellular processes, including cell growth, differentiation, and signaling pathways. The interest in PTPN20B has notably increased due to its potential involvement in cancer and other diseases. Unlike other well-characterized PTPs, PTPN20B exhibits unique structural features and regulatory mechanisms, which prompt researchers to investigate its function in depth. Studies have shown that PTPN20B can modulate insulin signaling and is implicated in metabolic disorders. Additionally, recent findings suggest that PTPN20B may have a role in the regulation of immune responses and could influence tumor microenvironments. The development of recombinant PTPN20B proteins provides a valuable tool for elucidating its enzymatic activity and biological functions. By producing and characterizing these proteins, researchers can explore how PTPN20B interacts with other cellular components, paving the way for potential therapeutic interventions targeting this phosphatase. Overall, the study of PTPN20B and its recombinant forms holds promise for advancing our understanding of its role in health and disease, making it a significant focus of current biomedical research.
