Analytical Data
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基因名
CD72
- Application
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别名
CD72;B-cell differentiation antigen CD72
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P21854
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表达区间
117-359aa
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氨基酸序列
RYLQVSQQLQ QTNRVLEVTN SSLRQQLRLK ITQLGQSAE DLQGSRRELA QSQEALQVEQ RAHQAAEGQL QACQADRQKT KETLQSEEQQ RRALEQKLSN MENRLKPFFT CGSADTCCPS GWIMHQKSCF YISLTSKNWQ ESQKQCETLS SKLATFSEIY PQSHSYYFLN SLLPNGGSGN SYWTGLSSNK DWKLTDDTQR TRTYAQSSKC NKVHKTWSWW TLESESCRSS LPYICEMTAF RFPD Fc(EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK)
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分子量
54 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD72 is a type II membrane protein that belongs to the Ig superfamily and is primarily expressed on the surface of B cells and some other immune cells. It plays a crucial role in modulating B cell activation and differentiation. The investigation of CD72 has garnered significant interest due to its involvement in various immune responses and potential implications in autoimmune diseases and cancer. Researchers have identified CD72 as an important co-regulatory molecule that influences the signaling pathways of B cells upon interaction with its ligands, such as CD5. The generation of recombinant CD72 protein is critical for elucidating its biological functions, understanding its interaction with other molecules, and exploring its therapeutic potential. By producing this recombinant protein, scientists can conduct detailed studies on its structure, function, and role in immune regulation. Additionally, such research can aid in the development of novel immunotherapeutic strategies targeting CD72, offering new avenues for treating diseases like lymphoma and autoimmune disorders. Overall, the study of CD72 recombinant protein is pivotal for advancing our understanding of B cell biology and the broader immune system, paving the way for innovative treatments in immunology.












