Cat: PA2000-2015

Recombinant Human Glxr Protein,His

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Analytical Data

  • Gene name

    Glxr

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Glxr;GLXR;Glyoxylate reductase/hydroxypyruvate reductase

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9UBQ7

  • Expression Region

    1-328aa

  • AA Sequence

    MRPVRLMKVF VTRRIPAEGR VALARAADCE VEQWDSDEPI PAKELERGVA GAHGLLCLLS DHVDKRILDA AGANLKVIST MSVGIDHLAL DEIKKRGIRV GYTPDVLTDT TAELAVSLLL TTCRRLPEAI EEVKNGGWTS WKPLWLCGYG LTQSTVGIIG LGRIGQAIAR RLKPFGVQRF LYTGRQPRPE EAAEFQAEFV STPELAAQSD FIVVACSLTP ATEGLCNKDF FQKMKETAVF INISRGDVVN QDDLYQALAS GKIAAAGLDV TSPEPLPTNH PLLTLKNCVI LPHIGSATHR TRNTMSLLAA NNLLAGLRGE PMPSELKL

  • Molecular Weight

    35.6 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

GLXR (glutathione-dependent peroxidase-like protein) is a novel protein that has garnered significant attention in the field of molecular biology and biochemistry due to its potential role in oxidative stress response and cellular signaling pathways. Research indicates that GLXR, similar to glutathione peroxidases, may help in the detoxification of reactive oxygen species (ROS), which are implicated in various pathological conditions, including cancer, neurodegenerative diseases, and aging. The re-structuring of GLXR through recombinant DNA technology has enabled scientists to produce this protein in host systems, allowing for detailed studies of its structure-function relationships, enzymatic activity, and interactions with other cellular components. Understanding the molecular mechanisms by which GLXR operates could provide new insights into its physiological and pathological roles, further establishing its potential as a therapeutic target. The ongoing research aims to elucidate the regulatory mechanisms of GLXR expression and activity, along with its implications in disease contexts, paving the way for innovative approaches in disease prevention and treatment.

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