Analytical Data
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基因名
GK2
- Application
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别名
GK2；GK2；N-acetylgalactosamine kinase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14410
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表达区间
2-553aa
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氨基酸序列
AAPKTAAVGPLVGAVVQGTNSTRFLVFNSKTAELLSHHKVELTQEFPKEGWVEQDPKEILQSVYECIARTCEKLDELNIDISNIKAVGVSNQRETTVIWDKLTGEPLYNAVVWLDLRTQTTVEDLSKKIPGNSNFVKSKTGLPLSTYFSAVKLRWMLDNVRNVQKAVEEGRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKELCDFFEIPMDLLPNVFSSSEIYGLIKTGALEGVPISGCLGDQCAALVGQMCFQEGQAKNTYGTGCFLLCNTGRKCVFSEHGLLTTVAYKLGREKPAYYALEGSVAIAGAVIRWLRDNLGIIETSGDIERLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGILCGLTQFTNKCHIAFAALEAVCFQTREILEAMNRDCGIPLRHLQVDGGMTNNKVLMQLQADILHIPVIKPFMPETTALGAAMAAGAAEGVSVWSLEPQALSVLRMERFEPQIQATESEIRYATWKKAVMKSMGWVTSQSPEGGDPSIFSSLPLGFFIVSSMVMLIGARYISGVP
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分子量
76.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of GK2 (Glycine Kinase 2) recombinant protein originates from the need to better understand its role in various biological processes, particularly in energy metabolism and neurotransmitter synthesis. GK2 is an enzyme involved in the phosphorylation of glycine to form phosphoglycine, a crucial step that influences cellular energy balance and signaling pathways. Research has indicated that altered GK2 activity may be linked to metabolic disorders and neurological diseases, prompting a closer examination of its biochemical properties and regulatory mechanisms. The ability to produce recombinant GK2 in vitro has enabled scientists to investigate its structure, function, and interaction with other cellular components, providing insights into its physiological roles and potential implications in disease states. Additionally, exploring GK2 as a therapeutic target could pave the way for novel treatments, as its modulation may offer a means to restore normal metabolic functions. As a result, the production and study of GK2 recombinant protein have become a significant focus in biochemistry and molecular biology, aiming to uncover the complexities of this enzyme and its contributions to health and disease. By harnessing advanced techniques in protein expression and purification, researchers are poised to elucidate the intricate mechanisms through which GK2 operates, establishing a foundation for future experimental and clinical applications.
