Analytical Data
-
Gene name
CTSL1
- Application
-
Alternative Names
CTSL1；C3orf8；NIF1；NIFL；CTD small phosphatase-like Protein
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P07711
-
Expression Region
114-288
-
AA Sequence
APRSVDW REKGYVTPVK NQGQCGSCWA FSATGALEGQ MFRKTGRLIS LSEQNLVDCS GPQGNEGCNG GLMDYAFQYV QDNGGLDSEE SYPYEATEES CKYNPKYSVA NDTGFVDIPK QEKALMKAVA TVGPISVAID AGHESFLFYK EGIYFEPDCS SEDMDHGVLV VGYGFEST
-
Molecular Weight
37.5 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CTSL1, or Cathepsin L1, is a lysosomal cysteine protease that plays a crucial role in numerous biological processes, including protein degradation, antigen presentation, and tissue remodeling. Recent studies have highlighted its significance in cancer progression and autoimmune diseases, where aberrant expression levels are linked to altered cell signaling pathways and immune responses. As a result, CTSL1 has emerged as a potential biomarker for various diseases and a target for therapeutic interventions. Researchers are particularly interested in the recombinant protein form of CTSL1, as it allows for detailed studies of its enzymatic activity, substrate specificity, and interaction with small molecules or inhibitors. By producing CTSL1 recombinantly, scientists can obtain a sufficient quantity of pure protein for in vitro experiments, facilitating the exploration of its role in physiological and pathological contexts. The ability to manipulate CTSL1 in experimental settings provides insights into its mechanisms of action, paving the way for potential drug development aimed at restoring normal function in diseases associated with dysfunctional CTSL1 activity. The study of CTSL1 not only enhances our understanding of lysosomal biology but also opens avenues for innovative therapeutic strategies in cancer and immune-related disorders.
