Analytical Data
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Gene name
PDILT
- Application
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Alternative Names
PDILT；Protein disulfide-isomerase-like Protein of the testis
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N807
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Expression Region
21-584aa
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AA Sequence
SPEVNAGVSSIHITKPVHILEERSLLVLTPAGLTQMLNQTRFLMVLFHNP SSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKAPE LKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFVI SRPLVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLD SVLVFKKGKIVNRQKLINDSTNKQELNRVIKQHLTDFVIEYNTENKDLIS ELHIMSHMLLFVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNG RVFKYFRVTEVDIPSVQILNLSSDARYKMPSDDITYESLKKFGRSFLSKN ATKHQSSEEIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKC KMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLMYLDRYPFFRLFPSGS QQAVLYKGEHTLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLAEE KEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKTSEEVVVVVAKPKG PPVQKKKPKVKEELVDHHHHHH
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Molecular Weight
66 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PDILT (Protein Disulfide Isomerase-Like Testis-Expressed Protein) is a member of the PDI family, primarily expressed in the testes and associated with sperm maturation and development. The importance of PDILT in male fertility has garnered significant attention, given its role in protein folding and disulfide bond formation, which are critical for the proper functioning of various proteins involved in reproductive processes. Dysregulation of PDILT expression has been linked to infertility issues in males, prompting researchers to investigate its potential as a biomarker for infertility and a target for therapeutic interventions. Recent studies have focused on the detailed mechanisms by which PDILT influences sperm quality and functionality, aiming to elucidate its interactions with other reproductive proteins and pathways. Understanding the structure and function of PDILT at the molecular level may open avenues for novel treatments for male infertility, and its exploration sheds light on the broader implications of protein disulfide isomerases in reproductive biology. As research continues to advance, PDILT represents a promising area for further investigation in both fundamental biology and clinical applications related to male reproductive health.
