Analytical Data
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Gene name
C14orf169
- Application
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Alternative Names
60S ribosomal Protein L8 histidine hydroxylase; C14orf169; Chromosome 14 open reading frame 169 ; Histone lysine demethylase NO66
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H6W3
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Expression Region
1-641 aa
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AA Sequence
MDGLQASAGPLRRGRPRRRRKPQPHSGSVLALPLRSRKIRKQLRSVVSRMAALRTQTLPSENSEESRVESTADDLGDALPGGAAVAAVPDAARREPYGHLGPAELLEASPAARSLQTPSARLVPASAPPARLVEVPAAPVRVVETSALLCTAQHLAAVQSSGAPATASGPQVDNTGGEPAWDSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLALN
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Molecular Weight
97.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C14orf169, also known as KCTD16, has garnered significant interest in the field of molecular biology and genetics due to its potential roles in various physiological processes and disease states. Originally identified through genomic studies, C14orf169 encodes a protein that is implicated in cellular signaling pathways and may influence cell proliferation, differentiation, and apoptosis. Its expression has been observed in multiple tissues, suggesting a broad range of biological functions. Recent research highlights its involvement in specific pathologies, including certain cancers and neurodevelopmental disorders, indicating that aberrations in its expression or function could have profound implications for disease mechanisms. The study of C14orf169 protein, particularly in its recombinant form, allows researchers to analyze its biochemical properties, understand its interactions with other cellular molecules, and explore its potential as a therapeutic target. Recombinant protein studies also facilitate the development of antibodies for diagnostic purposes and the investigation of its role in various cellular contexts. Overall, the characterization of C14orf169 is crucial for elucidating its contributions to human health and disease, paving the way for future research on targeted therapies and clinical applications. As researchers continue to unravel the complexities surrounding this protein, it may reveal novel insights into the intricate networks that govern cellular behavior and pathology.
