Analytical Data
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基因名
PRKCQ
- Application
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别名
Protein kinase C theta type. EC:2.7.11.13. nPKC-theta
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q04759
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表达区间
1-100 aa
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氨基酸序列
MSPFLRIGLSNFDCGSCQSCQGEAVNPYCAVLVKEYVESENGQMYIQKKPTMYPPWDSTFDAHINKGRVMQIIVKGKNVDLISETTVELYSLAERCRKNN
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分子量
36.74 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of PRKCQ (Protein Kinase C Theta), a member of the protein kinase C (PKC) family, has garnered significant interest due to its crucial role in various cellular processes, including signal transduction, immune response, and cancer progression. PRKCQ is predominantly expressed in T cells and is integral to the activation and proliferation of these immune cells, making it a key player in adaptive immunity. Dysregulation of PRKCQ has been implicated in autoimmune diseases and certain types of cancers, highlighting its potential as a therapeutic target. Additionally, its involvement in inflammatory signaling pathways underscores its relevance in both normal physiological and pathological conditions. The recombinant expression of PRKCQ protein allows for detailed studies of its biochemical properties, interaction with other signaling molecules, and functional assays, paving the way for a better understanding of its mechanisms in health and disease. Overall, research on PRKCQ not only enhances our comprehension of immune regulation but also opens new avenues for the development of targeted therapies in immune-related disorders and malignancies.
