Analytical Data
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Gene name
Reg2
- Application
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Alternative Names
Reg2;Pap2;Regenerating islet-derived Protein 3-alpha
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Species
Mouse
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q08731
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Expression Region
1-173aa
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AA Sequence
MAQNNVYLIL FLCLMFLSYS QGQVAEEDFP LAEKDLPSAK INCPEGANAY GSYCYYLIED RLTWGEADLF CQNMNAGHLV SILSQAESNF VASLVKESGT TASNVWTGLH DPKSNRRWHW SSGSLFLFKS WATGAPSTAN RGYCVSLTSN TAYKKWKDEN CEAQYSFVCK FRA
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Molecular Weight
18 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Reg2, also known as regenerating gene 2, is a member of the Reg family of proteins, which are known to play significant roles in regenerative processes, particularly within the pancreas and gastrointestinal tract. Initially identified in the context of pancreatic regeneration, Reg2 has garnered attention due to its involvement in cellular proliferation, differentiation, and anti-apoptotic activities. Research indicates that Reg2 can be upregulated in response to various stimuli, including injury and inflammation, suggesting its potential as a biomarker for tissue regeneration and repair. Studies have demonstrated that Reg2 may exert protective effects on pancreatic β-cells and promote recovery after acute insults, hinting at its therapeutic potential in diabetes management. Additionally, Reg2’s expression and function are linked to inflammatory bowel diseases and other gastrointestinal disorders, making it a candidate for further investigation in these contexts. Understanding the molecular mechanisms underlying Reg2's function could open avenues for novel therapeutic strategies aimed at enhancing tissue repair and mitigating disease progression. Consequently, ongoing research is focused on elucidating the signaling pathways involving Reg2, its regulatory networks, and the potential interactions with other growth factors and cytokines that govern its activity in various physiological and pathological settings. This emerging body of knowledge positions Reg2 as a significant player not only in regenerative medicine but also in understanding disease mechanisms and developing targeted interventions.











