Analytical Data
-
基因名
PRKACG
- Application
-
别名
cAMP-dependent protein kinase catalytic subunit gamma; KAPCG_HUMAN; KAPG ; PKA C gamma; PKA C-gamma; PKACg; PRKACG; Protein kinase cAMP dependent catalytic gamma; Serine (threonine) protein kinase
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P22612
-
表达区间
2-351 aa
-
氨基酸序列
GNAPAKKDT EQEESVNEFL AKARGDFLYR WGNPAQNTAS SDQFERLRTL GMGSFGRVML VRHQETGGHY AMKILNKQKV VKMKQVEHIL NEKRILQAID FPFLVKLQFS FKDNSYLYLV MEYVPGGEMF SRLQRVGRFS EPHACFYAAQ VVLAVQYLHS LDLIHRDLKP ENLLIDQQGY LQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAVGFPPFY ADQPIQIYEK IVSGRVRFPS KLSSDLKHLL RSLLQVDLTK RFGNLRNGVG DIKNHKWFAT TSWIAIYEKK VEAPFIPKYT GPGDASNFDD YEEEELRISI NEKCAKEFSE F
-
分子量
40.4 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PRKACG, or Protein Kinase A Catalytic Subunit Gamma, is a vital component of the Protein Kinase A (PKA) signaling pathway, which plays a critical role in various cellular processes, including metabolism, gene expression, and cell proliferation. Research on PRKACG has gained momentum due to its involvement in cancer biology and other diseases. Abnormal regulation of PKA can lead to significant pathological consequences; thus, studying PRKACG may provide insights into therapeutic targets for cancer treatment and other disorders linked to aberrant signaling pathways. Recent advancements in recombinant protein technology have enabled researchers to produce PRKACG in a purified form, facilitating detailed studies of its structure, function, and interactions with regulatory subunits and substrates. Understanding the biochemical properties and regulatory mechanisms of PRKACG at a molecular level can illuminate its role in health and disease, potentially leading to novel strategies for drug development. The exploration of PRKACG also offers opportunities to investigate its functional variations across different tissues and species, enhancing our knowledge of the evolutionary conservation of PKA signaling and its implications for cellular management and response to external stimuli.
