Analytical Data
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Gene name
C14orf115
- Application
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Alternative Names
C14orf115; Vertnin; vrtn; VRTN_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H8Y1
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Expression Region
1-702aa
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AA Sequence
MTSRNQLVQK VLQELQEAVE CEGLEGLIGA SLEAKQVLSS FTLPTCREGG PGLQVLEVDS VALSLYPEDA PRNMLPLVCK GEGSLLFEAA SMLLWGDAGL SLELRARTVV EMLLHRHYYL QGMIDSKVML QAVRYSLCSE ESPEMTSLPP ATLEAIFDAD VKASCFPSSF SNVWHLYALA SVLQRNIYSI YPMRNLKIRP YFNRVIRPRR CDHVPSTLHI MWAGQPLTSH FFRHQYFAPV VGLEEVEAEG APGVAPALPA LAPLSSPAKT LELLNREPGL SYSHLCERYS VTKSTFYRWR RQSQEHRQKV AARFSAKHFL QDSFHRGGVV PLQQFLQRFP EISRSTYYAW KHELLGSGTC PALPPREVLG MEELEKLPEE QVAEEELECS ALAVSSPGMV LMQRAKLYLE HCISLNTLVP YRCFKRRFPG ISRSTYYNWR RKALRRNPSF KPAPALSAAG TPQLASVGEG AVIPWKSEAE EGAGNATGED PPAPGELLPL RMPLSRWQRR LRRAARRQVL SGHLPFCRFR LRYPSLSPSA FWVWKSLARG WPRGLSKLQV PVPTLGKGGQ EAEEKQEKEA GRDVTAVMAP PVGASSEDVE GGPSREGALQ EGATAQGQPH SGPLLSQPVV AAAGGRDGRM LVMDMIATTK FKAQAKLFLQ KRFQSKSFPS YKEFSALFPL TARSTYYMWK RALYDGLTLV DG
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Molecular Weight
78.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C14orf115, also known as Chromosome 14 Open Reading Frame 115, is a relatively uncharacterized protein that has gained attention in recent years due to its potential implications in various biological processes and diseases. Research indicates that C14orf115 may play a role in cellular functions such as cell signaling, proliferation, and apoptosis, although its exact mechanisms remain largely unexplored. There is growing interest in understanding its involvement in pathological conditions, particularly in cancer and neurodegenerative diseases, where dysregulation of similar proteins often leads to tumorigenesis or neuronal deterioration. The generation of recombinant C14orf115 protein is critical for investigating its functional properties, interactions, and potential implications in disease models. By producing this protein in controlled laboratory settings, researchers can conduct detailed biochemical assays and structural studies, enabling the identification of its binding partners and downstream signaling pathways. Additionally, this research could contribute to the development of therapeutic strategies aimed at modulating C14orf115 activity in disease contexts. Understanding the biological significance of C14orf115 and its associated pathways may pave the way for novel insights into its role in health and disease, enhancing our overall knowledge of cellular biology and potentially leading to innovative treatment approaches.
