Analytical Data
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Gene name
PRDM4
- Application
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Alternative Names
MGC45046; PFM 1; PFM1; PR domain containing 4; PR domain containing protein 4; PR domain zinc finger protein 4; PR domain zinc finger protein PFM 1; PR domain zinc finger protein PFM1; PR domain-containing protein 4; PR/SET domain 4; PRDM 4; PRDM4; PRDM4_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UKN5
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Expression Region
1-801 aa
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AA Sequence
MHHRMNEMNL SPVGMEQLTS SSVSNALPVS GSHLGLAASP THSAIPAPGL PVAIPNLGPS LSSLPSALSL MLPMGIGDRG VMCGLPERNY TLPPPPYPHL ESSYFRTILP GILSYLADRP PPQYIHPNSI NVDGNTALSI TNNPSALDPY QSNGNVGLEP GIVSIDSRSV NTHGAQSLHP SDGHEVALDT AITMENVSRV TSPISTDGMA EELTMDGVAG EHSQIPNGSR SHEPLSVDSV SNNLAADAVG HGGVIPMHGN GLELPVVMET DHIASRVNGM SDSALSDSIH TVAMSTNSVS VALSTSHNLA SLESVSLHEV GLSLEPVAVS SITQEVAMGT GHVDVSSDSL SFVSPSLQME DSNSNKENMA TLFTIWCTLC DRAYPSDCPE HGPVTFVPDT PIESRARLSL PKQLVLRQSI VGAEVGVWTG ETIPVRTCFG PLIGQQSHSM EVAEWTDKAV NHIWKIYHNG VLEFCIITTD ENECNWMMFV RKARNREEQN LVAYPHDGKI FFCTSQDIPP ENELLFYYSR DYAQQIGVPE HPDVHLCNCG KECNSYTEFK AHLTSHIHNH LPTQGHSGSH GPSHSKERKW KCSMCPQAFI SPSKLHVHFM GHMGMKPHKC DFCSKAFSDP SNLRTHLKIH TGQKNYRCTL CDKSFTQKAH LESHMVIHTG EKNLKCDYCD KLFMRRQDLK QHVLIHTQER QIKCPKCDKL FLRTNHLKKH LNSHEGKRDY VCEKCTKAYL TKYHLTRHLK TCKGPTSSSS APEEEEEDDS EEEDLADSVG TEDCRINSAV YSADESLSAH K
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Molecular Weight
87.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PRDM4, also known as PRDI-BF1 or RIZ3, is a member of the PR domain-containing family of proteins, which play critical roles in various cellular processes including gene regulation, cell differentiation, and embryonic development. Research has shown that PRDM4 contributes to the transcriptional regulation of target genes involved in development and differentiation processes, particularly within the context of hematopoiesis and pluripotency. Its expression levels and patterns are crucial in regulating critical pathways, making it a significant focus in the study of stem cell biology and cancer. Abnormal expression or mutations in PRDM4 have been linked to various cancers and other diseases, suggesting its potential as a biomarker for cancer diagnosis and prognosis. The production of recombinant PRDM4 protein has become a vital tool for elucidating its functional mechanisms and interactions, enabling researchers to explore its role in different biological contexts. Understanding the structure and function of PRDM4 through recombinant protein studies can provide insights into therapeutic strategies for conditions associated with its dysregulation. This growing body of research underscores the importance of PRDM4 as a target for further investigation, aiming to unravel its complex role in health and disease.
