Analytical Data
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基因名
CTGF
- Application
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别名
CTGF；CTGF；HCS24；IGFBP8；CCN family member 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P29279
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表达区间
253-349aa
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氨基酸序列
MGKKCIRTPK ISKPIKFELS GCTSMKTYRA KFCGVCTDGR CCTPHRTTTL PVEFKCPDGE VMKKNMMFIK TCACHYNCPG DNDIFESLYY RKMYGDMA
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分子量
11 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a multifunctional protein that plays a crucial role in various biological processes, including cell proliferation, differentiation, and extracellular matrix formation. It is particularly significant in fibrotic diseases, wound healing, and tissue remodeling, making it a key target in therapeutic research. Elevated levels of CTGF are often associated with pathological conditions such as pulmonary fibrosis, diabetic nephropathy, and systemic sclerosis, highlighting its potential as a biomarker and therapeutic target. The recombinant CTGF protein has been extensively studied to understand its mechanisms of action and therapeutic potential. By producing and purifying CTGF in laboratory settings, researchers can investigate its effects on cell signaling pathways and tissue interactions. Furthermore, recombinant CTGF enables the development of engineered therapeutic strategies aimed at modulating its activity to either promote healing in fibrotic conditions or inhibit its effects in instances of excessive fibrosis. The ongoing research into CTGF not only enhances our understanding of its biological functions but also provides valuable insights for devising novel treatments for fibrotic diseases and improving tissue regeneration strategies.
