Analytical Data
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基因名
PPYR1
- Application
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别名
NPY4R; PPYR1; Neuropeptide Y receptor type 4; NPY4-R; Pancreatic polypeptide receptor 1; PP1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P50391
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氨基酸序列
MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRRLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNPI
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分子量
42.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PPYR1, or the neuropeptide Y receptor type 1, is part of the G-protein coupled receptor (GPCR) family and plays a crucial role in various physiological processes, including appetite regulation, circadian rhythm, and anxiety. Given its significant involvement in the central nervous system, PPYR1 has emerged as a potential therapeutic target for conditions such as obesity, stress-related disorders, and metabolic syndromes. The study of PPYR1 recombinant protein is critical for understanding its structure-function relationship and the molecular mechanisms underlying its signaling pathways. Through recombinant protein technology, researchers can produce PPYR1 in a controlled manner, facilitating the study of its biochemical properties, ligand binding characteristics, and interactions with other cellular proteins. This research is vital for developing drugs that could modulate PPYR1 activity, potentially leading to novel treatments for related health issues. Moreover, understanding the nuances of PPYR1's function via recombinant proteins can offer insights into GPCR biology in general, as this receptor family represents a significant portion of pharmacological targets in drug development. As such, advancements in the production and characterization of PPYR1 recombinant proteins will enhance our knowledge of this important receptor and support the design of innovative therapeutic strategies.
