Analytical Data
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基因名
C12orf45
- Application
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别名
C12orf45; CL045_HUMAN; Uncharacterized Protein C12orf45
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N5I9
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表达区间
1-185aa
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氨基酸序列
MEVHGKPKAS PSCSSPTRDS SGVPVSKELL TAGSDGRGGI WDRLLINSQP KSRKTSTLQT VRIERSPLLD QVQTFLPQMA RANEKLRKEM AAAPPGRFNI ENIDGPHSKV IQMDVALFEM NQSDSKEVDS SEESSQDSSE NSSESEDEDD SIPSEVTIDN IKLPNSEGGK GKIEVLDSPA SKKKK
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分子量
20 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C12orf45, also known as the chromosome 12 open reading frame 45, is a relatively lesser-known gene that has garnered attention in recent years due to its potential roles in various cellular processes and implications in human diseases. While the exact function of C12orf45 remains largely elusive, preliminary studies suggest that it may be involved in critical biological pathways, including cell proliferation, apoptosis, and stress response mechanisms. Importantly, mutations or dysregulation of this gene have been implicated in certain types of cancers, raising interest in its potential as a biomarker or therapeutic target. The production of recombinant C12orf45 protein is essential for elucidating its structure-function relationships and understanding its biological roles in health and disease. By utilizing methods such as cloning, expression in suitable host systems (e.g., bacterial or mammalian cells), and purification techniques, researchers aim to generate sufficient quantities of the protein for biochemical and functional assays. This research not only paves the way for advancing our understanding of C12orf45's roles in cancer biology but also contributes to the broader field of gene function analysis, providing insights that may lead to novel therapeutic approaches for diseases associated with its dysregulation. Ultimately, thorough investigation of C12orf45 and its recombinant protein may unlock new avenues for clinical applications, highlighting the importance of continued research into this enigmatic gene.












