Cat: PA2000-5937

Recombinant Human C12orf44 Protein,His

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Analytical Data

  • Gene name

    C12orf44

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ATG101; Atg13-interacting Protein; ATGA1_HUMAN; Autophagy-related Protein 101; C12orf44

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BSB4

  • Expression Region

    1-218aa

  • AA Sequence

    MNCRSEVLEV SVEGRQVEEA MLAVLHTVLL HRSTGKFHYK KEGTYSIGTV GTQDVDCDFI DFTYVRVSSE ELDRALRKVV GEFKDALRNS GGDGLGQMSL EFYQKKKSRW PFSDECIPWE VWTVKVHVVA LATEQERQIC REKVGEKLCE KIINIVEVMN RHEYLPKMPT QSEVDNVFDT GLRDVQPYLY KISFQITDAL GTSVTTTMRR LIKDTLAL

  • Molecular Weight

    25 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

C12orf44, also known as the "Chromosome 12 Open Reading Frame 44," is a gene located on human chromosome 12 that has garnered attention in recent biomedical research due to its potential involvement in various cellular processes and diseases. Preliminary studies suggest that C12orf44 may play a role in cellular signaling and regulation, potentially influencing cell proliferation and differentiation. The protein encoded by this gene is thought to be implicated in certain neurodevelopmental disorders, leading researchers to investigate its precise biological functions. Recombination and expression of C12orf44 in heterologous systems allow for a better understanding of its functional properties, interactions with other proteins, and its role in pathological conditions. Understanding the molecular mechanisms underlying the actions of C12orf44 could provide insights into its contribution to neurodevelopment and other related disorders, making it a relevant target for future therapeutic interventions. Therefore, the study of C12orf44 recombinant protein serves as a critical step in elucidating the biological significance of this gene, paving the way for further investigations into its clinical implications.

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