Analytical Data
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Gene name
POU6F1
- Application
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Alternative Names
POU6F1; BRN5; MPOU; TCFB1; POU domain; class 6; transcription factor 1; Brain-specific homeobox/POU domain protein 5; Brain-5; Brn-5; mPOU homeobox protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14863
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Expression Region
1-301 aa
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AA Sequence
MPGISSQILT NAQGQVIGTL PWVVNSASVA APAPAQSLQV QAVTPQLLLN AQGQVIATLA SSPLPPPVAV RKPSTPESPA KSEVQPIQPT PTVPQPAVVI ASPAPAAKPS ASAPIPITCS ETPTVSQLVS KPHTPSLDED GINLEEIREF AKNFKIRRLS LGLTQTQVGQ ALTATEGPAY SQSAICRFEK LDITPKSAQK LKPVLEKWLN EAELRNQEGQ QNLMEFVGGE PSKKRKRRTS FTPQAIEALN AYFEKNPLPT GQEITEIAKE LNYDREVVRV WFCNRRQTLK NTSKLNVFQI P
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Molecular Weight
63.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
POU6F1, a member of the POU (POU domain) transcription factor family, plays a critical role in the regulation of gene expression during development and cellular differentiation. Emerging research highlights its significance in the central nervous system, particularly concerning neural development, where it influences the proliferation and differentiation of neural stem cells. Targeting POU6F1 has garnered attention due to its potential implications in various neurological disorders and cancers. Understanding the molecular mechanisms by which POU6F1 operates could provide insights into pathophysiological conditions and open avenues for therapeutic intervention. Recent advancements in genetic engineering and recombinant protein technology have enabled the production of POU6F1 in heterologous systems, allowing for detailed biophysical and functional characterization. This research aims to elucidate the structure-function relationship of POU6F1 and its interactions with other critical proteins, contributing to a broader understanding of transcriptional regulation in health and disease. As studies continue to unfold, POU6F1 is recognized as a promising candidate for both fundamental research and applied biomedical approaches.
