Analytical Data
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基因名
BXDC2
- Application
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别名
Brix1; Brix; Bxdc2; Ribosome biogenesis Protein BRX1 homolog; Brix domain-containing Protein 2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9DCA5
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表达区间
1-353aa
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氨基酸序列
MAATKRKRRGGFAVQAKKPKRNEIDAEPPAKRHATAEEVEEEERDRIPGPVCKGKWKNKERILIFSSRGINFRTRHLMQDLRMLMPHSKADTKMDRKDKLFVINEVCEMKNCNKCIYFEAKKKQDLYMWLSNSPHGPSAKFLVQNIHTLAELKMTGNCLKGSRPLLSFDPAFDELPHYALLKELLIQIFSTPRYHPKSQPFVDHVFTFTILDNRIWFRNFQIIEEDAALVEIGPRFVLNLIKIFQGSFGGPTLYENPHYQSPNMHRRVIRSITAAKYREKQQVKDVQKLRKKEPKTLLPHDPTADVFVTPAEEKPIEIQWVKPEPKVDLKARKKRIYKRQRKMKQRMDSGKTK
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分子量
65.23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BXDC2, a member of the B-cell receptor (BCR) signaling pathway, plays a crucial role in the immune response, particularly in B-cell activation and differentiation. Researchers have become increasingly interested in the characterization and functional analysis of BXDC2, as it is implicated in various immunological disorders and cancers. The investigation of recombinant BXDC2 protein is essential for understanding its structure-function relationship, interactions with other molecular partners, and role in signal transduction. Advances in recombinant DNA technology have facilitated the production of BXDC2 in expression systems, allowing for detailed biochemical studies. These studies aim to elucidate the molecular mechanisms by which BXDC2 influences B-cell function and contributes to disease pathology. Furthermore, understanding the properties of BXDC2 could open avenues for therapeutic innovations, including targeted treatments for B-cell malignancies and autoimmune diseases. Overall, the research on BXDC2 recombinant protein holds significant promise for enhancing our understanding of immune regulation and developing novel therapeutic strategies.
