Analytical Data
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Gene name
STX7
- Application
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Alternative Names
STX7；Syntaxin-7
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15400
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Expression Region
2-238aa
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AA Sequence
SYTPGVGGDP AQLAQRISSN IQKITQCSVE IQRTLNQLGT PQDSPELRQQ LQQKQQYTNQ LAKETDKYIK EFGSLPTTPS EQRQRKIQKD RLVAEFTTSL TNFQKVQRQA AEREKEFVAR VRASSRVSGS FPEDSSKERN LVSWESQTQP QVQVQDEEIT EDDLRLIHER ESSIRQLEAD IMDINEIFKD LGMMIHEQGD VIDSIEANVE NAEVHVQQAN QQLSRAADYQ RKSRKTL
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Molecular Weight
30 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
STX7 (Syntaxin 7) is a member of the SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein family, which plays a crucial role in intracellular membrane trafficking and fusion processes. Research on STX7 has gained attention due to its involvement in various cellular functions, including endocytosis, exocytosis, and organelle communication. Studies have revealed that STX7 interacts with other SNARE proteins and is essential for the fusion of late endosomes with other organelles, such as lysosomes, which are vital for maintaining cellular homeostasis and processing cellular waste. Dysregulation of STX7 has been linked to several pathological conditions, including neurodegenerative diseases and immune disorders. Therefore, understanding the structure and function of STX7 is critical for elucidating its role in these diseases and may provide insights for potential therapeutic targets. Recombinant STX7 proteins have been produced for detailed biochemical and structural studies, facilitating investigations into its interaction with partner proteins and its role in membrane dynamics. Overall, the research on STX7 recombinant proteins is pivotal in clarifying the molecular mechanisms of membrane trafficking and identifying novel strategies for tackling diseases associated with its dysfunction.
