Analytical Data
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Gene name
CPB1
- Application
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Alternative Names
CPB1；Cytochrome P450 2B6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P15086
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Expression Region
16-417aa
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AA Sequence
HHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHS TVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHS YEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQN KPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVL PVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASR NPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS YAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDW AYDQGIRYSF TFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLYVDHHHHHH
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Molecular Weight
47 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CPB1, or carboxypeptidase B1, is a zinc-dependent metallopeptidase primarily involved in protein digestion and activation of proenzymes in the pancreatic context. The study of CPB1 has gained momentum due to its significant role in various physiological and pathological processes, including pancreatic disorders, obesity, and cancer. Researchers have highlighted the enzyme's potential as a biomarker for studying pancreatic function and disease progression, as altered levels of CPB1 can indicate pathological changes. Additionally, the recombinant production of CPB1 allows for the detailed investigation of its molecular structure, functional properties, and interactions with substrates and inhibitors. The recombinant protein can be utilized in both basic research and therapeutic applications, such as drug development aimed at targeting CPB1 to modulate its activity in diseases. Advances in molecular biology techniques have facilitated the efficient expression and purification of CPB1, enabling comprehensive studies on its enzymatic mechanisms and regulatory pathways. Overall, research on CPB1 not only enhances our understanding of enzymatic functions within the digestive system but also opens new avenues for clinical applications in diagnosing and treating related health conditions.
