Analytical Data
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基因名
PlGF2
- Application
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别名
D12S1900; Pgf; PGFL; PIGF; Placenta growth factor; Placental growth factor; Placental growth factor; vascular endothelial growth factor related protein; PlGF 2; PlGF; PLGF_HUMAN; PlGF2; SHGC 10760
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P49763
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表达区间
19-170 aa
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氨基酸序列
LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR
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分子量
17.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Placental growth factor 2 (PlGF-2) is a member of the vascular endothelial growth factor (VEGF) family, which plays a crucial role in angiogenesis, the formation of new blood vessels. It is primarily expressed in the placenta and is implicated in various physiological and pathological processes, including fetal development, wound healing, and inflammatory responses. Research on PlGF-2 has gained significant attention due to its potential applications in understanding and treating various diseases, such as cancer, cardiovascular disorders, and diabetic complications, where abnormal angiogenesis plays a pivotal role. The recombinant form of PlGF-2 has been developed to facilitate detailed studies of its biological functions and therapeutic potential. By producing PlGF-2 as a recombinant protein, researchers can investigate its mechanisms of action, interactions with receptors, and influence on endothelial cell behavior under controlled conditions. Additionally, the availability of recombinant PlGF-2 allows for the exploration of its implications in clinical settings, such as its role as a biomarker for certain diseases or as a target for novel therapeutic strategies aimed at modulating angiogenesis. This growing body of research underscores the importance of PlGF-2 in both basic science and translational medicine, paving the way for innovative treatments that harness its angiogenic properties.
