Analytical Data
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Gene name
Ngfb
- Application
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Alternative Names
Ngfb；NGFB；Beta-nerve growth factor
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P01138
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Expression Region
122-241aa
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AA Sequence
SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA
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Molecular Weight
27 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Ngfb, or Neuron Growth Factor beta, is a member of the neurotrophic factor family, known for its vital role in the development, maintenance, and survival of neurons. Researchers have been increasingly focused on Ngfb due to its potential therapeutic applications in neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease, where the loss of neuronal support leads to cognitive decline and motor dysfunction. The ability to modulate neuronal activity and promote growth through Ngfb presents opportunities for regenerative medicine and neuroprotection. Additionally, studies have shown that Ngfb can influence various cellular processes, including apoptosis, myelination, and synaptic plasticity, making it a crucial target for understanding brain health and disease. Advances in recombinant protein technology have enabled scientists to produce large quantities of Ngfb, allowing for in-depth studies of its mechanisms and interaction with other cellular pathways. Ongoing research aims to elucidate its functional effects in both in vitro and in vivo models, paving the way for therapeutic interventions that can harness its neuroprotective properties. As the understanding of Ngfb continues to grow, it holds promise for developing new strategies to combat neurological disorders by enhancing neuronal resilience and fostering repair processes.
