Analytical Data
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Gene name
PKNOX2
- Application
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Alternative Names
FLJ13074 ; Homeobox protein PKNOX2; Homeobox protein PREP 2; Homeobox protein PREP-2; PBX/knotted 1 homeobox 2; PBX/knotted homeobox 2; PKNOX2; PKNX2_HUMAN; PREP2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96KN3
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Expression Region
1-472 aa
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AA Sequence
MMQHASPAPA LTMMATQNVP PPPYQDSPQM TATAQPPSKA QAVHISAPSA AASTPVPSAP IDPQAQLEAD KRAVYRHPLF PLLTLLFEKC EQATQGSECI TSASFDVDIE NFVHQQEQEH KPFFSDDPEL DNLMVKAIQV LRIHLLELEK VNELCKDFCN RYITCLKTKM HSDNLLRNDL GGPYSPNQPS INLHSQDLLQ NSPNSMSGVS NNPQGIVVPA SALQQGNIAM TTVNSQVVSG GALYQPVTMV TSQGQVVTQA IPQGAIQIQN TQVNLDLTSL LDNEDKKSKN KRGVLPKHAT NIMRSWLFQH LMHPYPTEDE KRQIAAQTNL TLLQVNNWFI NARRRILQPM LDASNPDPAP KAKKIKSQHR PTQRFWPNSI AAGVLQQQGG APGTNPDGSI NLDNLQSLSS DSATMAMQQA MMAAHDDSLD GTEEEDEDEM EEEEEEELEE EVDELQTTNV SDLGLEHSDS LE
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Molecular Weight
52.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PKNOX2, a member of the knox family of homeobox genes, plays a crucial role in the regulation of various developmental processes, particularly in the context of neurogenesis and hematopoiesis. Researchers have increasingly focused on PKNOX2 due to its involvement in transcriptional regulation and potential implications in diseases such as cancer and neurodegenerative disorders. The protein's unique structure and function in cellular signaling pathways make it a valuable target for therapeutic exploration. By producing recombinant PKNOX2 protein, scientists aim to elucidate its biological functions, interactions with other molecular partners, and its impact on cellular processes. This research not only enhances our understanding of the molecular mechanisms underlying development and disease but also lays the groundwork for the development of novel therapeutic strategies that may leverage PKNOX2 modulation. The study of PKNOX2 is particularly significant in the context of regenerative medicine and targeted therapies, where manipulating gene expression at the protein level can lead to innovative approaches in treating various pathologies.
