Analytical Data
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基因名
TYRO3
- Application
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别名
TYRO3；BYK；Tyrosine-Protein kinase receptor TYRO3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q06418
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表达区间
455-890aa
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氨基酸序列
RKETRFGQAFDSVMARGEPAVHFRAARSFNRERPERIEATLDSLGISDEL KEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKA DIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILP FMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHR DLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESL ADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQP PECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQLSVLSASQDPLY INIERAEEPTAGGSLELPGRDQPYSGAGDGSGMGAVGGTPSDCRYILTPG GLAEQPGQAEHQPESPLNETQRLLLLQQGLLPHSSC
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分子量
77 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TYRO3, a member of the TAM receptor tyrosine kinase family, plays a crucial role in various physiological processes, including the regulation of immune responses, neuronal development, and tissue homeostasis. Research has indicated that TYRO3 is involved in the clearance of apoptotic cells and the modulation of inflammation, highlighting its potential as a therapeutic target in various diseases, such as cancer, autoimmune disorders, and neurodegenerative conditions. The interest in recombinant TYRO3 protein stems from its functional significance and the necessity to elucidate the molecular mechanisms underlying its signaling pathways. Recombinant expression systems enable the production of highly purified TYRO3 protein, facilitating structural and functional studies. Understanding the interactions of TYRO3 with its ligands and downstream signaling partners can provide insights into its role in cellular processes and disease mechanisms. Additionally, the potential for developing TYRO3-based therapeutics, including monoclonal antibodies or small molecules, makes studying this protein particularly important in the context of drug development. Overall, the research on TYRO3 recombinant protein paves the way for advancements in therapeutic strategies that aim to manipulate its signaling pathways for beneficial clinical outcomes.
