Analytical Data
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Gene name
TYRO3
- Application
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Alternative Names
TYRO3；BYK；Tyrosine-Protein kinase receptor TYRO3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q06418
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Expression Region
455-890aa
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AA Sequence
RKETRFGQAFDSVMARGEPAVHFRAARSFNRERPERIEATLDSLGISDEL KEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKA DIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILP FMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHR DLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESL ADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQP PECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQLSVLSASQDPLY INIERAEEPTAGGSLELPGRDQPYSGAGDGSGMGAVGGTPSDCRYILTPG GLAEQPGQAEHQPESPLNETQRLLLLQQGLLPHSSC
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Molecular Weight
77 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TYRO3, a member of the TAM receptor tyrosine kinase family, plays a crucial role in various physiological processes, including the regulation of immune responses, neuronal development, and tissue homeostasis. Research has indicated that TYRO3 is involved in the clearance of apoptotic cells and the modulation of inflammation, highlighting its potential as a therapeutic target in various diseases, such as cancer, autoimmune disorders, and neurodegenerative conditions. The interest in recombinant TYRO3 protein stems from its functional significance and the necessity to elucidate the molecular mechanisms underlying its signaling pathways. Recombinant expression systems enable the production of highly purified TYRO3 protein, facilitating structural and functional studies. Understanding the interactions of TYRO3 with its ligands and downstream signaling partners can provide insights into its role in cellular processes and disease mechanisms. Additionally, the potential for developing TYRO3-based therapeutics, including monoclonal antibodies or small molecules, makes studying this protein particularly important in the context of drug development. Overall, the research on TYRO3 recombinant protein paves the way for advancements in therapeutic strategies that aim to manipulate its signaling pathways for beneficial clinical outcomes.
